| Preparation and Catalytic Performance of a Novel Deep Eutectic Solvent in Green Multicomponent Reactions |
| کد مقاله : 1010-ICOC |
| نویسندگان |
|
آرزو منعم *1، داود حبیبی2 1دانشگاه بوعلی 2دانشگاه بوعلی سینا |
| چکیده مقاله |
| Deep eutectic solvents have countless advantages over normal solvents, and in addition to complying with the principles of green chemistry, depending on their nature, they can also act as catalysts. The use of deep eutectic solvents as acid catalysts has several advantages such as non‑toxicity, a catalytic effect similar to or higher than the acid itself, and the possibility of recovery and reuse without significant loss of activity. In this project, A novel deep eutectic solvent (MTPPBr–PCAT–DES) was prepared from a one‑to‑one mole ratio of methyltriphenyl‑phosphonium bromide (MTPPBr) and 3,4‑dihydroxybenzoic acid (PCAT = protocatechuic acid) and characterized by various techniques such as FT‑IR, TGA/DTA, densitometer, eutectic point, 1 H NMR, 13 C NMR and 31 P NMR. Then, it was used as a novel and capable catalyst for the synthesis of pyranopyrimidines from the multicomponent condensation reaction of barbituric acid, 4‑hydroxycoumarin, and aromatic aldehydes in mild conditions, short reaction times, and high yields. |
| کلیدواژه ها |
| Deep eutectic solvent, Green catalys, methyltriphenyl‑phosphonium bromide, Protocatechuic acid, Multicomponent reaction, Pyranopyrimidines |
| وضعیت: پذیرفته شده |