Synthesis and Application of a Polyaniline/PMAS Conducting Polymer Composite for the Selective Electrochemical Detection of Neurochemicals

کد مقاله : 1200-ICOC

نویسندگان

فاطمه قربانی *، فاطمه مصدرالامور، منصور عرب چم جنگلی دانشگاه صنعتی شاهرود

چکیده مقاله

Polyaniline (PANI) is a well-known conducting polymer characterized by good electrical conductivity, environmental stability, and high proton-doping capability. However, its electrochemical activity decreases significantly at higher pH values due to deprotonation and partial loss of the doped state. Incorporation of poly (2-methoxyaniline-5-sulfonic acid) (PMAS) as a self-doping acidic component enhances charge density and the number of electroactive sites while stabilizing PANI in its doped and electrochemically active form even under moderately alkaline conditions. The resulting PANI/PMAS composite film forms a stable, uniform, and conductive coating on the electrode surface, markedly improving electron-transfer kinetics and overall electrochemical performance [1]. Accurate determination of neurochemicals and biochemical is crucial in their biological applications. Here we present electrochemical detection of some aminoacids and neurochemicals such as tyrosine, metyonine, dopamine, acetaminophene etc. However, the bare glassy carbon electrode provides low sensitivity and poor signal definition because of slow electron-transfer kinetics. Therefore, the electrode was modified with a PANI/PMAS composite film by electrochemical polymerization of aniline in the presence of PMAS, and used for detection of dopamine (DA) and tyrosine (Tyr) which enhanced electron-transfer rates, resulting in sharper, more sensitive, and more reliable voltammetric signals (approximately 0.20 V for DA and 0.65 V for Tyr) for the analytes (Figure 1). The observed current is proportional to the concentration and the detection of the compounds can quantitativelybe perfomed in synthetic and real samples[2].

کلیدواژه ها

PANI, PMAS, Dopamine, Tyrosine.

وضعیت: پذیرفته شده