| Synthesis, characterization, and antibacterial evaluation of a novel Ag- incorporated LDH/UiO-66 MOF nanocomposite |
| کد مقاله : 1234-ICOC |
| نویسندگان |
|
مهدیه وزین فرد *1، شهرام مرادی دهقی1، ملک حمکتی خطبه سرا2، محمد یوسفی2 1دانشگاه آزاد اسلامی واحد تهران شمال، دپارتمان شیمی 2دانشگاه علوم پزشکی آزاد اسلامی تهران واحد علوم دارویی، دپارتمان شیمی |
| چکیده مقاله |
| Objective: Silver nanoparticles (AgNPs) are known to be effective substances with antibacterial properties, but their burst release affects their long-term use [1-2]. Methods: In this study, a new nanocomposite, Mg-Fe layered double hydroxide/Zr-metal-organic framework (Mg-Fe LDH/UiO-66 MOF), was prepared and then was coated with chitosan and cross-linked by glutaraldehyde. Subsequently, silver ions were deposited and reduced using Origanum vulgare extract, resulting in a uniform distribution of Ag nanoparticles within the hybrid. The prepared nanocomposite was characterized by XRD, FTIR, FESEM-EDX, and TEM techniques. Its antibacterial properties were evaluated via the disk diffusion method. Results and Conclusion: The Results showed good stability, sustained Ag⁺ release, and high antibacterial efficiency against Gram-positive and Gram-negative bacteria. |
| کلیدواژه ها |
| UiO-66 MOF, LDH, AgNPs, Antibacterial activity |
| وضعیت: پذیرفته شده |