| Mechanochemical Synthesis and catalytic application of MOF-303 for synthesis of Pyrido[2,3-d]pyrimidines derivatives |
| کد مقاله : 1308-ICOC |
| نویسندگان |
|
حسین احمدی *1، محمد علی زلفی گل2، مریم حجامی2 1ندارم 2استاد |
| چکیده مقاله |
| In recent decades, the design, synthesis and applications of porous catalyst such as metal-organic frameworks (MOFs) are one of the major subjects of research. This class of crystalline hybrid materials, composed of metal centers and various organic ligands, offers unique chemical versatility, a customizable framework, and exceptionally large and permanent internal porosity. The MOFs possess a high surface area, significant porosity, and the ability to chemically adjust through the modification of organic ligands, enhancing their efficacy as adsorbents, gas separation, catalysts, drug delivery and energy storage. The selection of an appropriate synthetic route plays a crucial role in designing MOFs with specific sizes, morphologies, and nanostructures. This necessity has spurred the development of new methods over the years. Recent advancements in MOF nanostructures have been propelled by the introduction of innovative synthetic approaches that enable precise control over size, morphology, and nanostructure. Pyrido[2,3-d]pyrimidines represent a heterocyclic ring system of considerable interest because of several biological activities associated with this scaffold. Some analogues have been found to act as anticancer agents inhibiting dihydrofolate reductases or tyrosine kinases, while others are known as antiviral agents. |
| کلیدواژه ها |
| Metal-Organic Frameworks, MOF-303, Pyrido[2,3-d]pyrimidines |
| وضعیت: پذیرفته شده |